What we have just published



Alessio N, Esposito G, Galano G, De Rosa R, Anello P, Peluso G, Tabocchini MA, Galderisi U. Irradiation of Mesenchymal Stromal Cells with Low and High Doses of  Alpha Particles Induces Senescence and/or Apoptosis. J Cell Biochem. 2017 Mar 2.  doi: 10.1002/jcb.25961. [Epub ahead of print] PubMed PMID: 28252222.

Mucerino S, Di Salle A, Alessio N, Margarucci S, Nicolai R, Melone MA, Galderisi U, Peluso G. Alterations in the carnitine cycle in a mouse model of Rett syndrome. Sci Rep. 2017 Feb 2;7:41824. doi: 10.1038/srep41824. PubMed PMID:  28150739; PubMed Central PMCID: PMC5288798.
Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone MA, Peluso G, Stuppia L, Galderisi U. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017 Jan 18. doi: 10.1002/jcp.25807. [Epub ahead of print] PubMed PMID: 28098348.

Alessio N, Özcan S, Tatsumi K, Murat A, Peluso G, Dezawa M, Galderisi U. The secretome of MUSE cells contains factors that may play a role in regulation of stemness, apoptosis and immunomodulation. Cell Cycle. 2017 Jan 2;16(1):33-44. doi: 10.1080/15384101.2016.1211215. Epub 2016 Jul 27. PubMed PMID: 27463232; PubMed Central PMCID: PMC5270533.
Forte A, Galderisi U, Cipollaro M, De Feo M, Corte AD. Epigenetic regulation of TGF-β1 signalling in dilative aortopathy of the thoracic ascending aorta. Clin Sci (Lond). 2016 Aug 1;130(16):1389-405. doi: 10.1042/CS20160222. Review. PubMed  PMID: 27389586.

Özcan S, Alessio N, Acar MB, Mert E, Omerli F, Peluso G, Galderisi U. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses. Aging (Albany NY). 2016 Jul;8(7):1316-29. doi: 10.18632/aging.100971. PubMed PMID: 27288264.
Ozkul Y, Galderisi U. The Impact of Epigenetics on Mesenchymal Stem Cell Biology. J Cell Physiol. 2016 Nov;231(11):2393-401. doi: 10.1002/jcp.25371. Epub  2016 Apr 4.  PubMed PMID: 26960183.
Alessio N, Capasso S, Di Bernardo G, Cappabianca S, Casale F, Calarco A, Cipollaro M, Peluso G, Galderisi U. Mesenchymal stromal cells having inactivated  RB1 survive following low irradiation and accumulate damaged DNA: hints for side  effects following radiotherapy. Cell Cycle. 2016 Apr 28:0. [Epub ahead of print]  PubMed PMID: 27124644.

Squillaro T, Peluso G, Galderisi U. Clinical Trials With Mesenchymal Stem Cells: An Update. Cell Transplant. 2016;25(5):829-48. doi: 10.3727/096368915X689622. Epub 2015 Sep 29. PubMed PMID: 26423725.

Özcan S, Alessio N, Acar MB, Toprak G, Gönen ZB, Peluso G, Galderisi U.  Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity. Oncotarget. 2015 Nov 24;6(37):39482-92. doi: 10.18632/oncotarget.5430. PubMed PMID: 26498687 

Alessio N, Del Gaudio S, Capasso S, Di Bernardo G, Cappabianca S, Cipollaro M, Peluso G, Galderisi U. Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process. Oncotarget. 2015 Apr 10;6(10):8155-66. PubMed PMID: 25544750; PubMed Central PMCID: PMC4480742.


It stemmed from the concept of gem cutting, which attempts to create as many replica watches symmetrical flat surfaces as possible to refract light. The more light which is refracted, the shinier the surfaces look, especially when shifted in the light. Basically replica watches what people do when they hold up a diamond or precious gem in an attempt to value it by judging the sparkle you see. Is this a good assessment of value? Maybe. Psychologically we are drawn to shiny objects. I am not sure why, but you can't deny it. Perhaps replica watches uk there is some bio-evolutionary function to it, but the bottom line is that we like our measures of wealth to be shiny much of the time. A fluted bezel, such as on Rolex replica watches, practically doubles the available flat polished surface area on the bezel. Allowing not only a greater surface for light refraction, but also the ability to reflect light replica watches sale from different angles as the same time.